Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104056 | 1.00 | THRA (0.51) | THRAMEN1KMT2AMAPTHTT | |
| SCHEMBL7100747 | 0.88 | ITGA4 (0.51) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL7100744 | 0.88 | ITGA4 (0.51) | MEN1KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL7102251 | 0.88 | ITGB1 (0.46) | MEN1KMT2AITGB3ITGB1ITGAV | |
| SCHEMBL7102248 | 0.88 | ITGB1 (0.46) | MEN1KMT2AITGB3ITGB1ITGAV | |
| SCHEMBL7098216 | 0.88 | ITGB1 (0.47) | MEN1KMT2AITGB3ITGB1ITGAV | |
| SCHEMBL7098218 | 0.88 | ITGB1 (0.47) | MEN1KMT2AITGB3ITGB1ITGAV | |
| SCHEMBL7105512 | 0.85 | MEN1 (0.44) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL7105509 | 0.85 | MEN1 (0.44) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL7105474 | 0.84 | NR1H4 (0.47) | MEN1KMT2ANPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |