SCHEMBL7104232

SCHEMBL7104232

O=P(Oc1ccccc1)(Oc1ccccc1Cl)Oc1ccccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
SRC P12931 1/20 0.45
PKM P14618 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 1/20 0.40
DPP4 P27487 1/20 0.40
HTT P42858 1/20 0.39
DRD2 P14416 1/20 0.39
DRD4 P21917 1/20 0.39
DRD3 P35462 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2980601 1.00 LMNA (0.58) LMNASMN1; SMN2POLBGAASRC
SCHEMBL2035293 0.90 LMNA (0.69) LMNASMN1; SMN2POLBGAAPKM
SCHEMBL343722 0.86 SRC (0.54) LMNASRCL3MBTL1TDP1CYP3A4
SCHEMBL9621941 0.84 CYP3A4 (0.41) LMNASMN1; SMN2POLBGAASRC
SCHEMBL9462195 0.83 LMNA (0.52) LMNASMN1; SMN2POLBGAAL3MBTL1
SCHEMBL8837400 0.82 LMNA (0.52) LMNAGAASRCL3MBTL1TDP1
SCHEMBL9493715 0.82 LMNA (0.64) LMNASMN1; SMN2POLBGAAPKM
SCHEMBL9834120 0.81 LMNA (0.55) LMNASMN1; SMN2POLBGAASRC
Triphenyl Phosphate SCHEMBL18116 0.81 SRC (0.64) LMNASRCL3MBTL1TDP1MAPK1
Triphenyl Phosphate SCHEMBL483692 0.81 SRC (0.64) LMNASRCL3MBTL1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4840881-A INCORPORATING OIL PARTICLES IN AT LEAST ONE LAYER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US claimed
US-20180104263-A1 BUTYRYLCHOLINESTERASE INHIBITORS JAL THERAPEUTICS, LLC 2018-04-19 US disclosed
US-20180104263-A1 BUTYRYLCHOLINESTERASE INHIBITORS JAL THERAPEUTICS, LLC 2018-04-19 US disclosed
EP-0620929-B1 PHOTOGRAPHIC DISPERSION EASTMAN KODAK CO (US) 2003-10-01 EP disclosed
EP-0823656-B1 Silver halide photographic light sensitive material KONISHIROKU PHOTO IND (JP) 2002-04-10 EP disclosed
US-5985530-A MULTILAYER PHOTOGRAPHIC FILM WITH COLLOID LAYER KONICA CORPORATION (JP) 1999-11-16 US disclosed
EP-0661588-B1 Color photographic element EASTMAN KODAK CO (US) 1999-10-20 EP disclosed
EP-0823656-A2 Silver halide photographic light sensitive material KONICA CORPORATION (JP) 1998-02-11 EP disclosed
US-5468604-A Particle growth inhibition EASTMAN KODAK COMPANY (US) 1995-11-21 US disclosed
EP-0661588-A2 Color photographic element EASTMAN KODAK COMPANY (US) 1995-07-05 EP disclosed
US-4153460-A Light-sensitive silver halide color photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD (JP) 1979-05-08 US disclosed
US-4148656-A SPIROCHROMAN COUPLERS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-04-10 US disclosed
US-4116696-A HYDROPHOBIC SUPPORT, HYDROPHILIC SUBBING AND PHOTOGRAPHIC LAYERS FUJI PHOTO FILM CO., LTD. (JP) 1978-09-26 US disclosed
US-4113488-A PHENOLIC COMPOUND AND SYNERGISTIC SULFIDE OR SULFOXIDE FUJI PHOTO FILM CO., LTD. (JP) 1978-09-12 US disclosed
US-4050938-A HYDROPHILIC COATINGS CONTAINING DYES OR DYE PRECURSORS EASTMAN KODAK COMPANY (US) 1977-09-27 US disclosed
US-4042394-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1977-08-16 US disclosed
US-4040836-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4040835-A Two-equivalent magenta couplers with amido coupling-off groups FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed
US-4032346-A 5-OXO-2-PYRAZOLIN-4-YL-AMINE-CARBODITHIOATE-DITHIOCARBONATE FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed
US-4009038-A CYAN COUPLER, A 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JA) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180104263-A1 BUTYRYLCHOLINESTERASE INHIBITORS BCHE, ACHE, PSEN1 LMNA 1641/4885SMN1; SMN2 178/4885POLB 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.