SCHEMBL9621941

SCHEMBL9621941

O=P(Oc1ccccc1)(Oc1ccccc1)Oc1ccc(OP(=O)(Oc2ccccc2)Oc2ccccc2)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
SRC P12931 1/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
HPGD P15428 1/20 0.39
POLB P06746 2/20 0.38
GAA P10253 1/20 0.38
INPPL1 O15357 1/20 0.37
INPP5A Q14642 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PNLIP P16233 1/20 0.37
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8837400 0.88 LMNA (0.52) CYP3A4SRCLMNAL3MBTL1TDP1
SCHEMBL7104232 0.84 LMNA (0.58) CYP3A4TSHRSRCLMNASMN1; SMN2
SCHEMBL2980601 0.84 LMNA (0.58) CYP3A4TSHRSRCLMNASMN1; SMN2
SCHEMBL25933703 0.79 CYP3A4 (0.50) CYP3A4TSHRSRCLMNAL3MBTL1
SCHEMBL131239 0.79 CYP3A4 (0.61) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL10015245 0.79 CYP3A4 (0.61) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL10015247 0.79 CYP3A4 (0.61) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL25933558 0.78 GPR84 (0.47) CYP3A4TSHRSRCL3MBTL1TDP1
SCHEMBL11541949 0.77 HPGD (0.59) CYP3A4TSHRSRCLMNASMN1; SMN2
SCHEMBL11553341 0.77 HPGD (0.59) CYP3A4TSHRSRCLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242830-A1 USE OF OILS COMPRISING NON-NEUROTOXIC ANTI-WEAR ADDITIVES NYCO (FR) 2023-08-03 US disclosed
US-5104450-A Films, molding materials; fireproof, plasticizing, stabilization, dimensional stability EASTMAN KODAK COMPANY (US) 1992-04-14 US disclosed