Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104334 | 1.00 | ATM (0.57) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL3731721 | 1.00 | ATM (0.57) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL3732044 | 0.90 | ATM (0.58) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL23750671 | 0.90 | ATM (0.58) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL3739194 | 0.87 | ATM (0.60) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL3741125 | 0.85 | CTSL (0.52) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL3729660 | 0.85 | CTSL (0.56) | ATMCTSKCTSLCTSSCTSB | |
| SCHEMBL5711207 | 0.82 | ATM (0.64) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL7675256 | 0.81 | ATM (0.50) | ATMCTSDCTSKCTSLCTSS | |
| SCHEMBL6026683 | 0.81 | ATM (0.50) | ATMCTSDCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186924-A1 | Prodrugs | MEDIVIR AB | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186924-A1 | Prodrugs | HAVCR2, CYP7A1, IGSF11 | ATM 4246/4885CTSD 3295/4885CTSK 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.