Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787406 | 0.86 | CTSB (0.51) | CTSKCTSBCTSLCTSSMEN1 | |
| SCHEMBL3739178 | 0.83 | ATM (0.55) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL3736148 | 0.82 | ATM (0.54) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL23750671 | 0.81 | ATM (0.58) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL3732044 | 0.81 | ATM (0.58) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL7104331 | 0.81 | ATM (0.57) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL7104334 | 0.81 | ATM (0.57) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL3731721 | 0.81 | ATM (0.57) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL3739194 | 0.79 | ATM (0.60) | ATMCTSDCTSKCTSBCTSL | |
| SCHEMBL3726951 | 0.79 | ATM (0.50) | ATMCTSDCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458772-B1 | Prodrugs | MEDIVIR AB (SE) | 2002-10-01 | — | — | US | disclosed |