SCHEMBL7104370

SCHEMBL7104370

CN(C(N)=O)C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
RECQL P46063 2/20 0.50
TSHR P16473 2/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
PARP1 P09874 1/20 0.50
CYP2C19 P33261 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HPGD P15428 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HSD11B1 P28845 1/20 0.48
TRPM8 Q7Z2W7 2/20 0.45
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 3/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11464381 1.00 MAPT (0.50) MAPTRECQLTSHRPOLBCYP3A4
Hydrochloric Acid SCHEMBL4562959 0.98 MAPT (0.48) MAPTRECQLTSHRPOLBCYP3A4
SCHEMBL2220361 0.86 ALDH1A1 (0.55) MAPTRECQLTSHRPOLBHPGD
SCHEMBL6651794 0.83 RECQL (0.46) MAPTRECQLTSHRPOLBCYP3A4
SCHEMBL11399080 0.82 HPGD (0.52) MAPTTSHRL3MBTL1HPGDALDH1A1
SCHEMBL11248983 0.82 RECQL (0.45) MAPTRECQLTSHRPOLBCYP3A4
SCHEMBL5338757 0.81 ALDH1A1 (0.48) TDP1HPGDALDH1A1RAB9ANPC1
SCHEMBL8166168 0.80 HPGD (0.50) MAPTRECQLTSHRPOLBHPGD
Hydrochloric Acid SCHEMBL11687441 0.80 HPGD (0.50) MAPTTSHRL3MBTL1HPGDALDH1A1
SCHEMBL1276163 0.79 HSD11B1 (0.53) MAPTRECQLTSHRPOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0936867-B1 BENZOYLPHENYLUREA INSECTICIDES AND METHODS OF USING CERTAIN BENZOYLPHENYLUREAS TO CONTROL COCKROACHES, ANTS, FLEAS, AND TERMITES DOW AGROSCIENCES LLC (US) 2003-03-05 EP disclosed
US-6303657-B1 APPLYING BENZOYLPHENYLUREA DERIVATIVE TO SOIL TO CONTROL TERMITES DOW AGROSCIENCES LLC 2001-10-16 US disclosed
US-6245816-B1 ALSO TERMITES, FLEAS, COCKROACHES SBRAGIA RONALD J (US) 2001-06-12 US disclosed
US-6221912-B1 Benzoylphenylurea insecticides and methods of using certain benzoylphenylureas to control cockroaches DOW AGROSCIENCES LLC 2001-04-24 US disclosed
US-6025397-A Method of using certain benzoylphenylureas to control fleas DOW AGROSCIENCES LLC (US) 2000-02-15 US disclosed
US-5945453-A Benzoylphenylurea insecticides to control cockroaches DOW AGROSCIENCES LLC (US) 1999-08-31 US disclosed
EP-0936867-A1 BENZOYLPHENYLUREA INSECTICIDES AND METHODS OF USING CERTAIN BENZOYLPHENYLUREAS TO CONTROL COCKROACHES, ANTS, FLEAS, AND TERMITES Dow AgroSciences LLC (US) 1999-08-25 EP disclosed
US-5886221-A TREATING WITH PESTICIDE, NONTOXIC TO DAPHNIA DOW AGROSCIENCES LLC (US) 1999-03-23 US disclosed
WO-1998019542-A1 NEW BENZOYLPHENYLUREA INSECTICIDES AND METHODS OF USING CERTAIN BENZOYLPHENYLUREAS TO CONTROL COCKROACHES, ANTS, FLEAS, AND TERMITES DOW AGROSCIENCES LLC (US) 1998-05-14 WO disclosed
US-4992544-A Intermediates for b-lactam antibiotics and b-lactamase inhibitor UNIVERSITY OF NOTRE DAME DU LAC (US) 1991-02-12 US disclosed
US-4198406-A Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith BEECHAM GROUP LIMITED (GB) 1980-04-15 US disclosed