Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31059309 | 1.00 | CXCR4 (0.61) | CXCR4 | |
| SCHEMBL31257251 | 0.84 | SLC40A1 (0.59) | CXCR4 | |
| SCHEMBL4760828 | 0.84 | SLC40A1 (0.59) | CXCR4 | |
| SCHEMBL3370850 | 0.84 | SLC40A1 (0.59) | CXCR4 | |
| SCHEMBL30338447 | 0.82 | CXCR4 (0.52) | CXCR4 | |
| SCHEMBL3409027 | 0.82 | CXCR4 (0.47) | CXCR4 | |
| SCHEMBL3408734 | 0.82 | CXCR4 (0.47) | CXCR4 | |
| SCHEMBL3406461 | 0.82 | CXCR4 (0.56) | CXCR4 | |
| SCHEMBL4881182 | 0.80 | CXCR4 (0.46) | CXCR4 | |
| SCHEMBL2509525 | 0.80 | CXCR4 (0.49) | CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317445-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022600-A2 | CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS | ANORMED INC. (CA) | 2002-03-21 | — | — | WO | disclosed |