Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099748 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL1289966 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL8130968 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL5422492 | 0.74 | KDM4E (0.43) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL6755336 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL8024526 | 0.71 | KDM4E (0.74) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL4626645 | 0.71 | CYP4F2 (0.51) | KDM4EALDH1A1GAABAZ2BBAZ2A | |
| SCHEMBL22641593 | 0.71 | ALDH1A1 (0.33) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL8643589 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL1290296 | 0.71 | HSP90AA1 (0.38) | KDM4EALDH1A1HPGDGLANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030171587-A1 | Antimicrobial 2-pyridones, their compositions and uses | THE PROCTER & GAMBLE COMPANY | 2003-09-11 | — | — | US | disclosed |
| EP-1341787-A2 | ANTIMICROBIAL 2-PYRIDONES, THEIR COMPOSITIONS AND USES | The Procter & Gamble Company (US) | 2003-09-10 | — | — | EP | disclosed |
| US-6509349-B1 | suppressing the growth or reproduction of microorganisms, such as bacteria. For example, such antibacterials and other antimicrobials are described in Antibiotics, Chemotherapeutics, and Antibacterial Agents for Disease | THE PROCTER & GAMBLE COMPANY | 2003-01-21 | — | — | US | disclosed |
| WO-2002048143-A2 | ANTIMICROBIAL 2-PYRIDONES, THEIR COMPOSITIONS AND USES | THE PROCTER & GAMBLE COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171587-A1 | Antimicrobial 2-pyridones, their compositions and uses | PIR, PRDX6, CLPP | KDM4E 4436/4885ALDH1A1 3730/4885HPGD 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.