SCHEMBL7104940

SCHEMBL7104940

O=C(O)c1ccc(C(=O)O)c(OCCO)c1OCCO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
RECQL P46063 1/20 0.45
GAA P10253 2/20 0.43
CYP1A2 P05177 1/20 0.42
KMT2A Q03164 3/20 0.40
PTK2B Q14289 1/20 0.40
PRKAB2 O43741 3/20 0.39
PRKAG1 P54619 3/20 0.39
PRKAA2 P54646 3/20 0.39
PRKAA1 Q13131 3/20 0.39
PRKAG3 Q9UGI9 3/20 0.39
PRKAG2 Q9UGJ0 3/20 0.39
PRKAB1 Q9Y478 3/20 0.39
CCNE2 O96020 1/20 0.39
CCNE1 P24864 1/20 0.39
CDK2 P24941 1/20 0.39
HSD17B10 Q99714 1/20 0.38
ALOX15 P16050 1/20 0.37
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11407285 0.85 MAPT (0.45) ALDH1A1GAAKMT2AHSD17B10ALOX15
SCHEMBL25432945 0.84 GAA (0.38) ALDH1A1RECQLGAAKMT2APRKAB2
SCHEMBL11076478 0.84 SELL (0.40) ALDH1A1RECQLGAASELLSELP
SCHEMBL6373411 0.84 ALDH1A1 (0.40) ALDH1A1RECQLGAAKMT2APTK2B
SCHEMBL1403627 0.82 CYP1A2 (0.46) ALDH1A1GAACYP1A2KMT2APTK2B
SCHEMBL9238401 0.81 ALDH1A1 (0.53) ALDH1A1RECQLGAAKMT2APTK2B
SCHEMBL11504333 0.81 WDR5 (0.53) ALDH1A1RECQLGAACCNE2CCNE1
SCHEMBL27841694 0.81 KMT2A (0.47) ALDH1A1CYP1A2KMT2ACCNE2CCNE1
SCHEMBL13951530 0.80 KMT2A (0.50) ALDH1A1RECQLKMT2APTK2BPRKAB2
SCHEMBL11340527 0.80 HNF4A (0.54) ALDH1A1RECQLGAAKMT2APTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020010303-A1 Novel melt-spun elastomeric fibers and the preparation thereof OPTIMER, INC. 2002-01-24 US claimed
US-6277942-B1 MAY BE KNIT OR WOVEN INTO TEXTILE ARTICLES SUCH AS HOSIERY AND PANTYHOSE AND SPORTSWEAR OPTIMER, INC. 2001-08-21 US claimed
EP-1021474-A4 ELASTOMERIC FIBERS AND PROCESS OF MAKING OPTIMER INC (US) 2000-12-06 EP claimed
EP-1021474-A1 ELASTOMERIC FIBERS AND PROCESS OF MAKING Optimer, Inc. (US) 2000-07-26 EP claimed
WO-1999014252-A1 ELASTOMERIC FIBERS AND PROCESS OF MAKING OPTIMER, INC. (US) 1999-03-25 WO claimed
US-5840233-A Process of making melt-spun elastomeric fibers OPTIMER, INC. (US) 1998-11-24 US claimed
EP-0679738-B1 Process for the production of spandex yarns BAYER AG (DE) 1998-08-05 EP claimed
EP-0679738-A1 Process for the production of spandex yarns BAYER AG (DE) 1995-11-02 EP claimed
US-20240043602-A1 POLYESTER POLYOL, URETHANE PREPOLYMER AND POLYURETHANE KURARAY CO., LTD. (JP) 2024-02-08 US disclosed
EP-4293061-A1 POLYESTER POLYOL, URETHANE PREPOLYMER AND POLYURETHANE Kuraray Co., Ltd. (JP) 2023-12-20 EP disclosed
US-6637181-B1 Having improved mechanical and thermal properties by using hydroxyalkyl-terminated polysiloxanes in combination with crosslinking-capable polyisocyanates in reaction with polymer diols with organic diisocyanates and diols BAYER AKTIENGESELLSCHAFT (DE) 2003-10-28 US disclosed
EP-1092052-B1 ELASTANE THREADS AND METHOD FOR THE PRODUCTION THEREOF BAYER AG (DE) 2003-09-10 EP disclosed
US-20020010303-A1 Novel melt-spun elastomeric fibers and the preparation thereof OPTIMER, INC. 2002-01-24 US disclosed
US-6277942-B1 MAY BE KNIT OR WOVEN INTO TEXTILE ARTICLES SUCH AS HOSIERY AND PANTYHOSE AND SPORTSWEAR OPTIMER, INC. 2001-08-21 US disclosed
WO-1999063138-A1 ELASTANE THREADS AND METHOD FOR THE PRODUCTION THEREOF BAYER AKTIENGESELLSCHAFT (DE) 1999-12-09 WO disclosed
WO-1999014252-A1 ELASTOMERIC FIBERS AND PROCESS OF MAKING OPTIMER, INC. (US) 1999-03-25 WO disclosed
US-5840233-A Process of making melt-spun elastomeric fibers OPTIMER, INC. (US) 1998-11-24 US disclosed
EP-0679738-B1 Process for the production of spandex yarns BAYER AG (DE) 1998-08-05 EP disclosed
US-5565270-A SOLVENT-FREE BAYER AKTIENGESELLSCHAFT (DE) 1996-10-15 US disclosed
EP-0679738-A1 Process for the production of spandex yarns BAYER AG (DE) 1995-11-02 EP disclosed