Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | ELOVL6 | Q9H5J4 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090477 | 0.84 | ENPP3 (0.64) | ELOVL6GLAENPP3ENPP1SMN1; SMN2 | |
| SCHEMBL712394 | 0.79 | ELOVL6 (0.52) | TP53ELOVL6ALDH1A1GLAENPP3 | |
| SCHEMBL708780 | 0.73 | ENPP3 (0.54) | TP53ELOVL6GLAENPP3ENPP1 | |
| SCHEMBL711630 | 0.71 | TP53 (0.46) | TP53ELOVL6ALDH1A1GLAENPP3 | |
| SCHEMBL2853568 | 0.71 | ENPP3 (0.54) | TP53ELOVL6ALDH1A1ENPP3ENPP1 | |
| SCHEMBL2846099 | 0.71 | ENPP3 (0.54) | TP53ELOVL6ALDH1A1ENPP3ENPP1 | |
| SCHEMBL13135944 | 0.71 | ENPP3 (0.54) | TP53ELOVL6ALDH1A1ENPP3ENPP1 | |
| SCHEMBL2846095 | 0.71 | ENPP3 (0.54) | TP53ELOVL6ALDH1A1ENPP3ENPP1 | |
| SCHEMBL2847007 | 0.70 | ELOVL6 (0.49) | TP53ELOVL6ALDH1A1ENPP3ENPP1 | |
| SCHEMBL2847008 | 0.70 | ELOVL6 (0.49) | TP53ELOVL6ALDH1A1ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124807-B2 | Sulfonyl-substituted 6-membered ring derivative | MSD K.K. (JP) | 2012-02-28 | — | — | US | disclosed |
| EP-2236494-A1 | SULFONYL SUBSTITUTED 6-MEMBERED RING DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-10-06 | — | — | EP | disclosed |
| US-20100249147-A1 | SULFONYL-SUBSTITUTED 6-MEMBERED RING DERIVATIVE | MSD K.K. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249147-A1 | SULFONYL-SUBSTITUTED 6-MEMBERED RING DERIVATIVE | CHRM2, CHRM3, CHRM1 | TP53 3099/4885ELOVL6 3399/4885ALDH1A1 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.