Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 7/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 7/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.61 |
| ▸ | STS | P08842 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712394 | 0.85 | ELOVL6 (0.52) | ENPP3ENPP1PTPN1ENPP2STS | |
| SCHEMBL710497 | 0.84 | TP53 (0.54) | ENPP3ENPP1PTPN1ENPP2STS | |
| SCHEMBL3188745 | 0.83 | ENPP3 (0.69) | ENPP3ENPP1PTPN1ENPP2STS | |
| SCHEMBL125695 | 0.82 | PTPN1 (0.89) | ENPP3ENPP1PTPN1ENPP2STS | |
| SCHEMBL28656982 | 0.82 | PTPN1 (0.89) | ENPP3ENPP1PTPN1ENPP2STS | |
| SCHEMBL5205624 | 0.81 | NPC1 (0.69) | ENPP3ENPP1PTPN1ENPP2STS | |
| SCHEMBL13090478 | 0.81 | ABL1 (0.64) | ENPP3ENPP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25647118 | 0.80 | PTPN1 (0.68) | ENPP3ENPP1PTPN1SMN1; SMN2HPGD | |
| SCHEMBL12545585 | 0.80 | PTPN1 (0.68) | ENPP3ENPP1PTPN1SMN1; SMN2HPGD | |
| SCHEMBL13973400 | 0.79 | ENPP3 (0.64) | ENPP3ENPP1PTPN1ENPP2STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236494-A1 | SULFONYL SUBSTITUTED 6-MEMBERED RING DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-10-06 | — | — | EP | disclosed |