SCHEMBL71052

SCHEMBL71052

O=C(Oc1ccccc1)c1nc[nH]c1C(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.47
KDM4E B2RXH2 3/20 0.46
LMNA P02545 2/20 0.44
GAA P10253 3/20 0.43
NR4A2 P43354 1/20 0.43
HSD17B10 Q99714 2/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 2/20 0.42
ALOX15 P16050 1/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
NSD2 O96028 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CYP1A2 P05177 1/20 0.40
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18208736 0.76 ALDH1A1 (0.43) ALDH1A1GAAHSD17B10POLBMAPT
SCHEMBL28728618 0.70 HAO1 (0.47) ALDH1A1KDM4EHSD17B10HPGDALOX15
SCHEMBL1081091 0.69 LMNA (0.54) ALDH1A1KDM4ELMNAGAAPOLB
SCHEMBL5742204 0.69 KDM4E (0.53) ALDH1A1KDM4ELMNAGAAHSD17B10
SCHEMBL11836426 0.68 KMT2A (0.47) ALDH1A1KDM4ENR4A2HSD17B10HPGD
SCHEMBL69045 0.68 ALDH1A1 (0.65) ALDH1A1KDM4ELMNANR4A2HSD17B10
SCHEMBL27726532 0.68 TP53 (0.53) ALDH1A1KDM4ELMNAGAANR4A2
SCHEMBL68414 0.67 TDP1 (0.66) ALDH1A1KDM4ELMNAHSD17B10POLB
SCHEMBL8619456 0.67 ALDH1A1 (0.56) ALDH1A1KDM4ELMNAGAAHSD17B10
SCHEMBL1081092 0.67 KDM4E (0.54) ALDH1A1KDM4ELMNAGAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALDH1A1 1882/4885KDM4E 717/4885LMNA 2207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.