Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 7/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105446 | 1.00 | MEN1 (0.46) | MEN1KMT2ANPSR1KDM4ECCR2 | |
| SCHEMBL7098080 | 0.93 | FPR2 (0.46) | MEN1KMT2ANPSR1KDM4ECCR2 | |
| SCHEMBL7098083 | 0.93 | FPR2 (0.46) | MEN1KMT2ANPSR1KDM4ECCR2 | |
| SCHEMBL7098706 | 0.88 | MEN1 (0.45) | MEN1KMT2ANPSR1PKM | |
| SCHEMBL7098708 | 0.88 | MEN1 (0.45) | MEN1KMT2ANPSR1PKM | |
| SCHEMBL7098692 | 0.87 | ITGB1 (0.47) | MEN1KMT2ANPSR1 | |
| SCHEMBL7098694 | 0.87 | ITGB1 (0.47) | MEN1KMT2ANPSR1 | |
| SCHEMBL7105450 | 0.86 | ITGB1 (0.54) | — | |
| SCHEMBL7102026 | 0.86 | ITGB1 (0.54) | — | |
| SCHEMBL7098043 | 0.84 | ITGB1 (0.51) | MEN1KMT2ANPSR1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |