Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705786 | 0.89 | CYP2C19 (0.45) | HSD17B10GPR119ATMCACNA1BBIRC2 | |
| SCHEMBL7772191 | 0.84 | EPHX2 (0.41) | HSD17B10GPR119ATMMMP13MEN1 | |
| SCHEMBL7770775 | 0.83 | EPHX2 (0.44) | HSD17B10GPR119ATMMMP13TSHR | |
| SCHEMBL7774527 | 0.82 | MEN1 (0.43) | HSD17B10ATMCACNA1BBIRC2MEN1 | |
| SCHEMBL7105548 | 0.81 | HSD17B10 (0.39) | HSD17B10GPR119ATMCACNA1BBIRC2 | |
| SCHEMBL7110494 | 0.79 | CACNA1B (0.50) | HSD17B10ATMCACNA1BBIRC2MEN1 | |
| SCHEMBL7111673 | 0.78 | YAP1 (0.46) | HSD17B10ATMCACNA1B | |
| SCHEMBL7772734 | 0.77 | SMN1; SMN2 (0.44) | CACNA1BBIRC2MEN1KMT2AMAPT | |
| SCHEMBL5364041 | 0.77 | CACNA1B (0.54) | HSD17B10GPR119ATMCACNA1BBIRC2 | |
| SCHEMBL7109137 | 0.77 | HSD17B10 (0.42) | HSD17B10ATMCACNA1BBIRC2HTRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | ONO PHARMACEUTICAL CO., LTD. | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013725-A1 | Amino acid derivatives | CACNA1B, SCN1A, SCN2A | HSD17B10 1544/4885GPR119 833/4885ATM 3517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.