Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP7 | P09237 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP8 | P22894 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772191 | 0.92 | EPHX2 (0.41) | EPHX2KMT2AMEN1HSD17B10ABL1 | |
| SCHEMBL7774527 | 0.88 | MEN1 (0.43) | KMT2AMEN1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL7105883 | 0.83 | HSD17B10 (0.45) | KMT2AMEN1HSD17B10GPR119TSHR | |
| SCHEMBL7105591 | 0.82 | MEN1 (0.43) | KMT2AMEN1HSD17B10ALDH1A1ATM | |
| SCHEMBL7110901 | 0.82 | MEN1 (0.43) | KMT2AMEN1HSD17B10ALDH1A1ATM | |
| SCHEMBL7110470 | 0.82 | MEN1 (0.43) | KMT2AMEN1HSD17B10ALDH1A1ATM | |
| SCHEMBL6705786 | 0.81 | CYP2C19 (0.45) | HSD17B10ALDH1A1GPR119SMN1; SMN2ATM | |
| SCHEMBL5113474 | 0.79 | CACNA1B (0.50) | EPHX2KMT2AMEN1HSD17B10ABL1 | |
| SCHEMBL7105628 | 0.78 | MEN1 (0.45) | KMT2AMEN1HSD17B10ALDH1A1POLB | |
| SCHEMBL5113479 | 0.77 | EPHX2 (0.46) | EPHX2KMT2AMEN1ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090912-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-04-11 | — | — | EP | disclosed |