Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC5R | P33032 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770775 | 0.92 | EPHX2 (0.44) | EPHX2HSD17B10ABL1RIN1POLB | |
| SCHEMBL7105883 | 0.84 | HSD17B10 (0.45) | HSD17B10POLBATMMAPTKMT2A | |
| SCHEMBL6705786 | 0.82 | CYP2C19 (0.45) | HSD17B10ATMALDH1A1GPR119 | |
| SCHEMBL7774527 | 0.80 | MEN1 (0.43) | HSD17B10ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL5117829 | 0.78 | CACNA1B (0.47) | EPHX2HSD17B10ABL1RIN1ATM | |
| SCHEMBL5117831 | 0.77 | EPHX2 (0.43) | EPHX2HSD17B10ABL1RIN1POLB | |
| SCHEMBL7110901 | 0.74 | MEN1 (0.43) | HSD17B10ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7105591 | 0.74 | MEN1 (0.43) | HSD17B10ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7110470 | 0.74 | MEN1 (0.43) | HSD17B10ATMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7105221 | 0.73 | ATM (0.39) | HSD17B10POLBATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090912-A1 | AMINO ACID DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-04-11 | — | — | EP | disclosed |