Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2867397 | 0.79 | PNMT (0.37) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL2873716 | 0.79 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL7752720 | 0.77 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Heptane SCHEMBL27620248 | 0.77 | PNMT (0.36) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL8632818 | 0.76 | PNMT (0.35) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL2837143 | 0.76 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL2839955 | 0.75 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL618215 | 0.72 | PNMT (0.50) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL29479988 | 0.72 | PNMT (0.50) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL646564 | 0.71 | PNMT (0.39) | PNMTDRD2DRD4DRD3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786466-B1 | Olefin polymerisation process which comprises a transition metal catalyst. | TOSOH CORP (JP) | 2003-04-16 | — | — | EP | disclosed |