Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | CRHBP | P24387 | 2/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710607 | 1.00 | MAPT (0.34) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL709596 | 0.90 | MEN1 (0.31) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL709595 | 0.90 | MEN1 (0.31) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL705540 | 0.87 | NPSR1 (0.36) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL705541 | 0.87 | NPSR1 (0.36) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL702579 | 0.73 | OGA (0.39) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL704812 | 0.73 | MEN1 (0.33) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL704811 | 0.73 | MEN1 (0.33) | MAPTLMNAMEN1KMT2AGAA | |
| SCHEMBL711443 | 0.72 | KDM4E (0.39) | POLBHPGD | |
| SCHEMBL703955 | 0.71 | PIK3CA (0.32) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |