Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711444 | 0.85 | CHEK2 (0.35) | HPGD | |
| SCHEMBL711442 | 0.85 | CHEK2 (0.35) | HPGD | |
| SCHEMBL701907 | 0.77 | KDM4E (0.37) | KDM4EPARP1 | |
| SCHEMBL701908 | 0.77 | KDM4E (0.37) | KDM4EPARP1 | |
| SCHEMBL651234 | 0.77 | HPGD (0.48) | KDM4EPOLBHPGDHRH3 | |
| SCHEMBL710608 | 0.72 | MAPT (0.34) | POLBHPGD | |
| SCHEMBL710607 | 0.72 | MAPT (0.34) | POLBHPGD | |
| SCHEMBL708157 | 0.72 | SYK (0.35) | ADORA2AADORA1HRH3PARP1 | |
| SCHEMBL10176546 | 0.69 | HPGD (0.48) | KDM4EPOLBHPGDHRH3 | |
| SCHEMBL705496 | 0.66 | PIK3CA (0.37) | KDRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |