Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106376 | 1.00 | PDK1 (0.43) | PDK1PDK2PDK3PDK4KMT2A | |
| SCHEMBL5458354 | 0.77 | KDM4C (0.47) | KMT2AMEN1KDM4CL3MBTL1KCNA5 | |
| SCHEMBL7103094 | 0.74 | PDK1 (0.46) | PDK1PDK2PDK3PDK4RAB9A | |
| SCHEMBL14135410 | 0.74 | MEN1 (0.47) | KMT2AMEN1KDM4CL3MBTL1HPGD | |
| SCHEMBL9570948 | 0.73 | KDM4C (0.49) | KMT2AMEN1KDM4CL3MBTL1KCNA5 | |
| SCHEMBL7101982 | 0.72 | KCNA5 (0.36) | KMT2AMEN1KDM4CL3MBTL1KCNA5 | |
| SCHEMBL8575515 | 0.72 | MGLL (0.35) | KMT2AMEN1KDM4CL3MBTL1KCNA5 | |
| SCHEMBL7101987 | 0.72 | KCNA5 (0.36) | KMT2AMEN1KDM4CL3MBTL1KCNA5 | |
| SCHEMBL16979834 | 0.70 | KDM4C (0.49) | KMT2AMEN1KDM4CL3MBTL1KCNA5 | |
| SCHEMBL7272362 | 0.70 | KDM4C (0.49) | KMT2AMEN1KDM4CL3MBTL1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6353025-B1 | COMPOUNDS AS DRUGS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |