Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | RECQL | P46063 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172412 | 0.98 | TDP1 (0.50) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL28878142 | 0.82 | TDP1 (0.52) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL921090 | 0.82 | TDP1 (0.52) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL1397101 | 0.82 | PTGS1 (0.68) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL29948126 | 0.82 | TDP1 (0.52) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL283463 | 0.82 | TDP1 (0.52) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL29657745 | 0.82 | TDP1 (0.52) | TDP1TP53KDM4EMAPTRECQL | |
| SCHEMBL19117132 | 0.82 | HSD17B1 (0.55) | TDP1TP53KDM4ERECQLLMNA | |
| SCHEMBL29525823 | 0.81 | TDP1 (0.65) | TDP1KDM4EMAPTRECQLLMNA | |
| SCHEMBL241136 | 0.81 | TDP1 (0.65) | TDP1KDM4EMAPTRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836628-B1 | PROCESS FOR PREPARING POLYHYDROXYSTYRENE WITH A NOVOLAK TYPE STRUCTURE | TRIQUEST L P (US) | 2003-10-15 | — | — | EP | claimed |