Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | BACE1 | P56817 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
| ▸ | DBH | P09172 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717670 | 0.98 | ESR1 (0.65) | ESR1ESR2BACE1MAPTKDM4E | |
| SCHEMBL29720481 | 0.87 | ESR1 (0.74) | ESR1ESR2BACE1MAPTKDM4E | |
| SCHEMBL1924746 | 0.87 | ESR1 (0.74) | ESR1ESR2BACE1MAPTKDM4E | |
| SCHEMBL2913327 | 0.86 | ESR1 (0.61) | ESR1ESR2BACE1MAPTKDM4E | |
| SCHEMBL529618 | 0.83 | ESR1 (0.68) | ESR1ESR2TP53TDP1ALOX15 | |
| SCHEMBL68664 | 0.83 | ESR1 (0.68) | ESR1ESR2TP53TDP1ALOX15 | |
| SCHEMBL12949979 | 0.81 | ESR1 (0.65) | ESR1ESR2TP53TDP1ALOX15 | |
| SCHEMBL8402779 | 0.81 | ESR1 (0.65) | ESR1ESR2TP53TDP1ALOX15 | |
| SCHEMBL10626367 | 0.81 | MAPT (0.65) | ESR1ESR2BACE1MAPTKDM4E | |
| SCHEMBL16065724 | 0.81 | ESR1 (0.65) | ESR1ESR2TP53TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836628-B1 | PROCESS FOR PREPARING POLYHYDROXYSTYRENE WITH A NOVOLAK TYPE STRUCTURE | TRIQUEST L P (US) | 2003-10-15 | — | — | EP | claimed |