SCHEMBL2913327

SCHEMBL2913327

Cc1cc(CCCO)ccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.61
ESR2 Q92731 2/20 0.61
IGF1R P08069 6/20 0.52
ALOX15 P16050 6/20 0.52
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX5 P09917 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
BACE1 P56817 1/20 0.50
TP53 P04637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
SLC28A3 Q9HAS3 1/20 0.44
BCHE P06276 1/20 0.44
CA2 P00918 1/20 0.43
SKP2 Q13309 1/20 0.43
AR P10275 1/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
MAPK1 P28482 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68664 0.90 ESR1 (0.68) ESR1ESR2IGF1RALOX15TP53
SCHEMBL529618 0.90 ESR1 (0.68) ESR1ESR2IGF1RALOX15TP53
SCHEMBL6227927 0.88 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL3717670 0.88 ESR1 (0.65) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL16065724 0.88 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL8402779 0.88 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL12949979 0.88 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
Methyl Alcohol SCHEMBL7106415 0.86 ESR1 (0.63) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL1924746 0.85 ESR1 (0.74) ESR1ESR2IGF1RALOX15KDM4E
SCHEMBL29720481 0.85 ESR1 (0.74) ESR1ESR2IGF1RALOX15KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639324-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2023-05-02 US disclosed
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
CN-1307139-C Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2007-03-28 CN disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
CN-1448379-A Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2003-10-15 CN disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed
US-5266673-A Compatibilizer for polymer blends and alloys MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 ESR1 1976/4885ESR2 351/4885IGF1R 3333/4885
US-11639324-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition DCXR, LCT, MLEC ESR1 4604/4885ESR2 4869/4885IGF1R 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.