SCHEMBL8675334

SCHEMBL8675334

O=C(Oc1ccccc1)C(Cl)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.56
ATM Q13315 2/20 0.56
ELANE P08246 1/20 0.43
MGLL Q99685 1/20 0.42
KMT2A Q03164 2/20 0.42
PTGS1 P23219 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
HPGD P15428 2/20 0.41
LMNA P02545 2/20 0.41
CYP2D6 P10635 2/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SRC P12931 1/20 0.40
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MAPK1 P28482 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13979835 0.89 L3MBTL1 (0.46) L3MBTL1ATMKMT2ALMNAMEN1
SCHEMBL4981318 0.83 L3MBTL1 (0.44) L3MBTL1ATMELANEMGLLKMT2A
SCHEMBL6554232 0.81 ATM (0.52) L3MBTL1ATMELANEKMT2ATDP1
SCHEMBL7106510 0.81 KMT2A (0.47) L3MBTL1KMT2ATDP1HPGDLMNA
SCHEMBL6305898 0.81 ATM (0.52) L3MBTL1ATMELANEKMT2ATDP1
SCHEMBL22616417 0.81 ATM (0.45) L3MBTL1ATMELANEMGLLKMT2A
SCHEMBL6844397 0.79 L3MBTL1 (0.44) L3MBTL1ATMKMT2ATDP1LMNA
SCHEMBL6839974 0.79 L3MBTL1 (0.44) L3MBTL1ATMKMT2ATDP1LMNA
SCHEMBL11603067 0.79 L3MBTL1 (0.59) L3MBTL1ATMELANEMGLLKMT2A
SCHEMBL2516637 0.79 L3MBTL1 (0.59) L3MBTL1ATMELANEMGLLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542836-B1 POLYMERIZATION OF SELECTED VINYL MONOMERS DU PONT (US) 1995-11-29 EP claimed
EP-0542836-A1 POLYMERIZATION OF SELECTED VINYL MONOMERS. DU PONT (US) 1993-05-26 EP claimed
WO-1992002562-A1 POLYMERIZATION OF SELECTED VINYL MONOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-20 WO claimed
US-5086137-A Polymerization of acrylic acids, esters and/or chloroprene using a diazoats or cyanate catalyst and a halogenated nitrile , ester or ketone activator E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-04 US claimed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP claimed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US claimed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP claimed
CN-116568677-A piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers 探戈医药股份有限公司 2023-08-08 CN disclosed
CN-106963514-A Urinary device 科洛普拉斯特公司 2017-07-21 CN disclosed
US-5728911-A CATALYTIC SOLUTION COPOLYMERIZATION OF ETHYLENE WITH POLYUNSATURATED MONOMER DSM COPOLYMER, INC. (US) 1998-03-17 US disclosed
EP-0705284-B1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1997-07-09 EP disclosed
EP-0705284-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM NV (NL) 1996-04-10 EP disclosed
EP-0542836-B1 POLYMERIZATION OF SELECTED VINYL MONOMERS DU PONT (US) 1995-11-29 EP disclosed
WO-1995000564-A1 PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE DSM N.V. (NL) 1995-01-05 WO disclosed
EP-0542836-A1 POLYMERIZATION OF SELECTED VINYL MONOMERS. DU PONT (US) 1993-05-26 EP disclosed
WO-1992002562-A1 POLYMERIZATION OF SELECTED VINYL MONOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-20 WO disclosed
US-5086137-A Polymerization of acrylic acids, esters and/or chloroprene using a diazoats or cyanate catalyst and a halogenated nitrile , ester or ketone activator E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-02-04 US disclosed
EP-0044119-B1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE STAMICARBON B.V. (NL) 1985-05-29 EP disclosed
US-4435552-A COORDINATION CATALYST CONTAINING HALOACYL COMPOUND STAMICARBON B.V. (NL) 1984-03-06 US disclosed
EP-0044119-A2 Process for the preparation of copolymers of ethylene with at least one other 1-alkene STAMICARBON B.V. (NL) 1982-01-20 EP disclosed