Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27667379 | 0.86 | CTBP2 (0.47) | CTBP2MAOAMAOBPKMRAB9A | |
| SCHEMBL8995861 | 0.81 | SIRT5 (0.41) | PKMALDH1A1 | |
| SCHEMBL872658 | 0.81 | NPC1 (0.52) | CTBP2PKMRAB9ANPC1SHBG | |
| SCHEMBL29498164 | 0.81 | NPC1 (0.52) | CTBP2PKMRAB9ANPC1SHBG | |
| SCHEMBL6258617 | 0.81 | TTR (0.67) | CXCL8MAPK1KMT2A | |
| SCHEMBL27833130 | 0.80 | CTBP2 (0.49) | CTBP2MAOBNPC1SHBGALDH1A1 | |
| Hydrochloric Acid SCHEMBL27455925 | 0.80 | NPC1 (0.50) | CTBP2PKMRAB9ANPC1SHBG | |
| SCHEMBL11260981 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KMT2A | |
| SCHEMBL265672 | 0.79 | CTBP2 (0.55) | CTBP2MAOAMAOBPKMRAB9A | |
| SCHEMBL513530 | 0.79 | PKM (0.53) | CTBP2PKMSHBGALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792936-B1 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | MITSUBISHI CHEM CORP (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-5841001-A | ALLOWING 2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL TO CONTACT ENZYME STEREOSELECTIVELY CATALYZING ESTER INTERCHANGE IN PRESENCE OF CARBOXYLIC ANHYDRIDE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0792936-A2 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | Mitsubishi Chemical Corporation (JP) | 1997-09-03 | — | — | EP | disclosed |
| US-4865648-A | ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE | KITO TSUTOMU (JP) | 1989-09-12 | — | — | US | disclosed |