Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | EPOR | P19235 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109965 | 0.77 | FFAR1 (0.45) | FFAR1FFAR4 | |
| SCHEMBL7107404 | 0.76 | EPOR (0.47) | CACNA1BMMP1MMP2MMP9MMP12 | |
| SCHEMBL7109248 | 0.76 | EPOR (0.47) | CACNA1BMMP1MMP2MMP9MMP12 | |
| SCHEMBL7107759 | 0.73 | MMP1 (0.47) | TRPM8MMP1MMP2MMP9MMP12 | |
| SCHEMBL7111904 | 0.72 | EPOR (0.46) | CTDSP1PTGIRMMP1MMP2MMP9 | |
| Tert-Butylamine SCHEMBL7109741 | 0.72 | EPOR (0.43) | CACNA1BEPOR | |
| SCHEMBL9718462 | 0.71 | FFAR1 (0.61) | FFAR1FFAR4LTB4RLTB4R2 | |
| SCHEMBL7105131 | 0.70 | MAOB (0.51) | MMP1MMP2MMP9MMP12EPOR | |
| SCHEMBL7105126 | 0.70 | EPOR (0.46) | PTGIRPTGDREPOR | |
| SCHEMBL7112435 | 0.70 | MAOB (0.51) | MMP1MMP2MMP9MMP12EPOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |