Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.35 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597236 | 0.86 | DPP4 (0.40) | F2PRSS1PRSS2PRSS3FKBP1A | |
| SCHEMBL2226082 | 0.84 | DPP4 (0.46) | F2PRSS1PRSS2PRSS3FKBP1A | |
| SCHEMBL14336163 | 0.83 | DPP4 (0.45) | F2PRSS1PRSS2PRSS3FKBP1A | |
| SCHEMBL9603823 | 0.81 | DPP4 (0.44) | F2PRSS1PRSS2PRSS3FKBP1A | |
| Acetic Acid SCHEMBL3507728 | 0.79 | F2 (0.41) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL1498278 | 0.78 | F2 (0.42) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL12955580 | 0.78 | F2 (0.44) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL9396036 | 0.78 | DPP4 (0.43) | F2PRSS1PRSS2PRSS3FKBP1A | |
| SCHEMBL9120650 | 0.78 | DPP4 (0.38) | F2PRSS1PRSS2PRSS3DPP4 | |
| Hydrochloric Acid SCHEMBL11528157 | 0.78 | F2 (0.42) | F2PRSS1PRSS2PRSS3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | F2 1/4885PRSS1 43/4885PRSS2 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.