Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803790 | 1.00 | ALDH1A1 (0.49) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL14940598 | 0.91 | ALOX5 (0.55) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL15926259 | 0.89 | CYP1A2 (0.48) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL22927612 | 0.86 | ALOX5 (0.45) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL14952240 | 0.86 | ALOX5 (0.45) | ALDH1A1TDP1ALOX5TSHREPHX2 | |
| SCHEMBL14944798 | 0.86 | DGKA (0.53) | ALOX5TSHREPHX2PRKCAPRKCE | |
| SCHEMBL10084982 | 0.86 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL11045151 | 0.86 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL11045194 | 0.86 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 | |
| SCHEMBL11045153 | 0.86 | ALOX5 (0.60) | ALDH1A1ALOX15TDP1USP2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343746-A1 | CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002050013-A1 | CARBOXYLIC ACID COMPOUND HAVING CYCLOPROPANE RING | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-27 | — | — | WO | disclosed |