Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRS3 | P32247 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3549036 | 1.00 | CNR2 (0.51) | CNR2L3MBTL1ADORA3ADORA1ADORA2A | |
| SCHEMBL8619535 | 0.83 | ADORA3 (0.49) | CNR2L3MBTL1ADORA3ADORA1ADORA2A | |
| SCHEMBL11696118 | 0.75 | ALDH1A1 (0.64) | L3MBTL1HPGDSMN1; SMN2EPHX2HSD17B10 | |
| SCHEMBL11695375 | 0.75 | L3MBTL1 (0.52) | L3MBTL1HPGDSMN1; SMN2EPHX2HSD17B10 | |
| SCHEMBL29560792 | 0.74 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AGPR183GBA1 | |
| SCHEMBL15102267 | 0.74 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AGPR183GBA1 | |
| SCHEMBL15124922 | 0.74 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AGPR183GBA1 | |
| SCHEMBL19068532 | 0.74 | NPC1 (0.49) | ADORA3ADORA1ADORA2AGPR183HPGD | |
| SCHEMBL16391919 | 0.73 | ABCG2 (0.49) | ADORA3ADORA1ADORA2AGPR183GBA1 | |
| SCHEMBL6483634 | 0.73 | CNR2 (0.43) | CNR2HPGDSMN1; SMN2GBA1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909762-B1 | Binuclear Iridium(I) phosphine complexes and their use as catalysts for the asymmetric hydroamination of olefins | LONZA AG (CH) | 2003-04-09 | — | — | EP | disclosed |
| EP-0909762-A2 | Binuclear Iridium(I) phosphine complexes and their use as catalysts for the asymmetric hydroamination of olefins | LONZA A.G. (CH) | 1999-04-21 | — | — | EP | disclosed |