Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103433 | 0.83 | L3MBTL1 (0.41) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL7103648 | 0.81 | POLB (0.46) | L3MBTL1HTTKDM4EMAPTGAA | |
| SCHEMBL7110289 | 0.81 | LMNA (0.44) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL16122493 | 0.80 | L3MBTL1 (0.47) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL7104581 | 0.80 | LMNA (0.43) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL7107441 | 0.78 | LMNA (0.41) | L3MBTL1LMNAKDM4EMAPTGAA | |
| SCHEMBL25930508 | 0.76 | L3MBTL1 (0.48) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL9829371 | 0.76 | L3MBTL1 (0.43) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL7103561 | 0.76 | L3MBTL1 (0.43) | L3MBTL1LMNAHTTKDM4EMAPT | |
| SCHEMBL6809927 | 0.75 | L3MBTL1 (0.50) | L3MBTL1LMNAKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6353025-B1 | COMPOUNDS AS DRUGS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |