Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PPID | Q08752 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107961 | 0.87 | CYP4F2 (0.48) | L3MBTL1SMN1; SMN2TSHRCYP4F2CYP4A11 | |
| SCHEMBL7105502 | 0.84 | GAA (0.38) | L3MBTL1SMN1; SMN2TSHRCYP4F2CYP4A11 | |
| SCHEMBL7103146 | 0.84 | TOP2A (0.47) | SMN1; SMN2TSHRCYP4F2CYP4A11KDM4E | |
| SCHEMBL7103433 | 0.83 | L3MBTL1 (0.41) | L3MBTL1SMN1; SMN2CYP4F2CYP4A11HTT | |
| SCHEMBL7110289 | 0.83 | LMNA (0.44) | L3MBTL1SMN1; SMN2TSHRCYP4F2CYP4A11 | |
| SCHEMBL7107186 | 0.80 | MAT2A (0.32) | TSHRHTTKDM4EGAAALDH1A1 | |
| SCHEMBL7107066 | 0.76 | L3MBTL1 (0.42) | L3MBTL1SMN1; SMN2CYP4F2CYP4A11HTT | |
| SCHEMBL7102017 | 0.75 | POLB (0.56) | L3MBTL1SMN1; SMN2TSHRCYP4F2CYP4A11 | |
| SCHEMBL7103171 | 0.75 | CA12 (0.40) | L3MBTL1SMN1; SMN2TSHRCYP4F2CYP4A11 | |
| SCHEMBL9832125 | 0.75 | ABCB1 (0.47) | L3MBTL1SMN1; SMN2HTTKDM4ENLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-B1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2003-09-24 | — | — | EP | disclosed |
| US-6353025-B1 | COMPOUNDS AS DRUGS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |