Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRG | P23470 | 2/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10159905 | 0.76 | AKR1C2 (0.49) | NR1H4TSHRBLMRARBAKR1C2 | |
| SCHEMBL7107210 | 0.75 | EPHX2 (0.48) | PTPRGPNMTTSHRMEN1RECQL | |
| SCHEMBL7033732 | 0.73 | SSTR3 (0.55) | GAAHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5797654 | 0.72 | PNMT (0.46) | PTPRGPTPRCPNMTGAAHTT | |
| SCHEMBL1712181 | 0.72 | NR1H4 (0.50) | GAANR1H4APEX1MEN1RECQL | |
| SCHEMBL107902 | 0.71 | HMGB1 (0.58) | NR1H4KMT2ARARB | |
| SCHEMBL10160064 | 0.71 | AKR1C2 (0.58) | PNMTNR1H4TSHRBLMRARB | |
| SCHEMBL7037133 | 0.71 | CCR3 (0.46) | PNMTMEN1KMT2A | |
| SCHEMBL1627397 | 0.70 | NR1H4 (0.51) | NR1H4TSHRRARBSMN1; SMN2 | |
| SCHEMBL4439324 | 0.70 | PNMT (0.53) | PNMTTSHRHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | CBR3, CBR1, CYP2E1 | PTPRG 2297/4885PTPRC 3807/4885PNMT 2784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.