Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPRG | P23470 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034125 | 0.84 | EPHX2 (0.49) | EPHX2TSHRSRD5A2S1PR5HAO1 | |
| SCHEMBL7107214 | 0.75 | PTPRG (0.43) | EPHX2TSHRHAO1SMN1; SMN2PTPRG | |
| SCHEMBL366289 | 0.74 | HAO1 (0.67) | EPHX2TSHRSRD5A2HAO1NPC1 | |
| SCHEMBL7037113 | 0.72 | TSHR (0.51) | EPHX2TSHRSRD5A2S1PR5HAO1 | |
| SCHEMBL6481933 | 0.72 | MEN1 (0.65) | EPHX2TSHRSRD5A2HAO1NPC1 | |
| SCHEMBL4439324 | 0.70 | PNMT (0.53) | TSHRHAO1FFAR1PNMTKMO | |
| SCHEMBL9781682 | 0.69 | KMO (0.56) | TSHRMEN1KMT2APNMTKMO | |
| SCHEMBL27810623 | 0.69 | RARB (0.61) | TSHRMEN1KMT2A | |
| SCHEMBL9246404 | 0.68 | KMO (0.53) | TSHRPTPRGFFAR1MEN1RECQL | |
| SCHEMBL9414680 | 0.68 | MMP12 (0.54) | TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | HOECHST SCHERING AGREVO S.A. (FR) | 2003-12-04 | — | — | US | disclosed |
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 2002-06-06 | — | — | US | disclosed |
| EP-1003714-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999001422-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068838-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | CBR1, CBR3, CYP2E1 | EPHX2 69/4885TSHR 331/4885SRD5A2 40/4885 |
| US-20030225302-A1 | Aromatic amides, their preparation process and their use as pesticides | CBR3, CBR1, CYP2E1 | EPHX2 157/4885TSHR 140/4885SRD5A2 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.