Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.56 |
| ▸ | CA1 | P00915 | 6/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94896 | 0.80 | CA1 (0.46) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL22762259 | 0.76 | ALDH1A1 (0.44) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL8101287 | 0.75 | MMP12 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL4449191 | 0.75 | CA1 (0.44) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL92354 | 0.75 | CA1 (0.44) | CA2CA1CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29269900 | 0.74 | TAAR1 (0.47) | CA2CA1CA9 | |
| SCHEMBL22265816 | 0.73 | ALDH1A1 (0.51) | CA2CA1CA9BLMALDH1A1 | |
| SCHEMBL11022222 | 0.73 | CA1 (0.43) | CA2CA1CA9 | |
| SCHEMBL31269816 | 0.72 | KMT2A (0.55) | CA2CA1CA9ALDH1A1 | |
| SCHEMBL10228461 | 0.72 | CA1 (0.41) | CA2CA1CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345591-A1 | PHARMACEUTICAL AEROSOL FORMULATION | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002049616-A1 | PHARMACEUTICAL AEROSOL FORMULATION | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |