Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.91 |
| ▸ | GAA | P10253 | 1/20 | 0.91 |
| ▸ | TSHR | P16473 | 1/20 | 0.91 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.91 |
| ▸ | HTT | P42858 | 1/20 | 0.91 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.58 |
| ▸ | RXRA | P19793 | 4/20 | 0.58 |
| ▸ | RXRB | P28702 | 4/20 | 0.58 |
| ▸ | RXRG | P48443 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Felbinac SCHEMBL26084 | 0.96 | LMNA (1.00) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28601196 | 0.94 | LMNA (0.88) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284672 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284674 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284752 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL384892 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28286223 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL8844919 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28286222 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 | |
| Felbinac SCHEMBL28284677 | 0.93 | LMNA (0.95) | LMNAABCC4GAATSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032578-A1 | Antifungal and antiparasitic compounds | UNITED STATES GOVERNMENT | 2003-02-13 | — | — | US | disclosed |
| US-6403576-B1 | CHOLESTEROL SYNTHESIS INHIBITOR | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2002-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032578-A1 | Antifungal and antiparasitic compounds | PIGO, CAT, ERG28 | LMNA 3993/4885ABCC4 312/4885GAA 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.