Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108356 | 0.85 | KDM4E (0.74) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7108298 | 0.83 | KDM4E (0.72) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7108302 | 0.81 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL18713108 | 0.81 | KDM4E (0.68) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL14190802 | 0.80 | KDM4E (0.76) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL7530265 | 0.79 | KDM4E (0.74) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL14479131 | 0.79 | KDM4E (0.73) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5471150 | 0.79 | MEN1 (0.75) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL15515225 | 0.77 | KDM4E (0.63) | KDM4EHRH3MEN1KMT2ANPSR1 | |
| SCHEMBL5800630 | 0.77 | KDM4E (0.69) | KDM4EHRH3MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030170173-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2003-09-11 | — | — | US | disclosed |
| EP-1283728-A2 | CONTRAST AGENTS | Amersham Health AS (NO) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001089584-A2 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030170173-A1 | Contrast agents | GBA1, RNASE1, MAN2B1 | KDM4E 4578/4885HRH3 2413/4885MEN1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.