SCHEMBL7107849

SCHEMBL7107849

Nc1cc(Cl)c(OC(F)(F)C(F)C(F)(F)F)c(Cl)c1F

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7028225 0.80 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10MEN1USP2
SCHEMBL9501334 0.79 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10MEN1USP2
SCHEMBL7701776 0.73 MEN1 (0.43) ALDH1A1TSHRHSD17B10MEN1USP2
SCHEMBL29408804 0.73 MEN1 (0.43) ALDH1A1TSHRHSD17B10MEN1USP2
SCHEMBL9489918 0.73 MAPT (0.36) ALDH1A1TSHRHSD17B10MEN1USP2
SCHEMBL17961012 0.70 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10RECQL
SCHEMBL7709838 0.69
SCHEMBL9587803 0.68 CYP3A4 (0.39) ALDH1A1TSHRMEN1MAPTKMT2A
SCHEMBL9755710 0.68 SCN9A (0.36) ALDH1A1HSD17B10MEN1USP2MAPT
SCHEMBL6555055 0.67 RECQL (0.40) ALDH1A1TSHRHSD17B10MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0936867-B1 BENZOYLPHENYLUREA INSECTICIDES AND METHODS OF USING CERTAIN BENZOYLPHENYLUREAS TO CONTROL COCKROACHES, ANTS, FLEAS, AND TERMITES DOW AGROSCIENCES LLC (US) 2003-03-05 EP disclosed
US-6303657-B1 APPLYING BENZOYLPHENYLUREA DERIVATIVE TO SOIL TO CONTROL TERMITES DOW AGROSCIENCES LLC 2001-10-16 US disclosed
US-6245816-B1 ALSO TERMITES, FLEAS, COCKROACHES SBRAGIA RONALD J (US) 2001-06-12 US disclosed
US-6221912-B1 Benzoylphenylurea insecticides and methods of using certain benzoylphenylureas to control cockroaches DOW AGROSCIENCES LLC 2001-04-24 US disclosed
US-6025397-A Method of using certain benzoylphenylureas to control fleas DOW AGROSCIENCES LLC (US) 2000-02-15 US disclosed
US-5886221-A TREATING WITH PESTICIDE, NONTOXIC TO DAPHNIA DOW AGROSCIENCES LLC (US) 1999-03-23 US disclosed