SCHEMBL9501334

SCHEMBL9501334

Nc1cc(F)c(OC(F)(F)C(F)C(F)(F)F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RECQL P46063 1/20 0.31
MEN1 O00255 1/20 0.30
USP2 O75604 1/20 0.30
MAPT P10636 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107849 0.79 ALDH1A1 (0.33) ALDH1A1TSHRHSD17B10RECQLMEN1
SCHEMBL17961012 0.76 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10RECQL
SCHEMBL9560252 0.74 ALDH1A1 (0.34) ALDH1A1TSHRHSD17B10RECQLALOX15
SCHEMBL7760349 0.74 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10RECQLMEN1
SCHEMBL7797155 0.74 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10RECQLMEN1
SCHEMBL7028225 0.70 ALDH1A1 (0.37) ALDH1A1TSHRHSD17B10RECQLMEN1
SCHEMBL9488794 0.70 ALDH1A1 (0.47) ALDH1A1TSHRHSD17B10RECQLMEN1
SCHEMBL9616203 0.68 RECQL (0.35) ALDH1A1TSHRHSD17B10RECQLMEN1
SCHEMBL20149143 0.66 HSD17B10 (0.38) ALDH1A1TSHRHSD17B10MAPT
SCHEMBL20149146 0.66 ALOX5AP (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0327504-B1 N-BENZOYL-N'-TRIFLUOROPHENYLUREAS, THEIR PREPARATION AND USE FOR THE CONTROL OF PESTS CIBA-GEIGY AG (CH) 1993-05-12 EP disclosed
EP-0327504-A1 N-Benzoyl-N'-trifluorophenylureas, their preparation and use for the control of pests CIBA-GEIGY AG (CH) 1989-08-09 EP disclosed