SCHEMBL7701776

SCHEMBL7701776

Nc1cc(Cl)c(OC(F)(F)C(F)C(F)(F)F)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
KMT2A Q03164 1/20 0.43
GAA P10253 2/20 0.41
NPC1 O15118 1/20 0.39
RECQL P46063 1/20 0.37
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408804 1.00 MEN1 (0.43) MEN1USP2MAPTALOX15KMT2A
SCHEMBL10935563 0.89 GAA (0.44) MEN1USP2MAPTALOX15KMT2A
SCHEMBL10936394 0.86 GAA (0.41) MEN1USP2MAPTALOX15KMT2A
SCHEMBL10763129 0.85 MEN1 (0.36) MEN1USP2MAPTALOX15KMT2A
SCHEMBL26696690 0.82 NPC1 (0.50) MEN1USP2MAPTALOX15KMT2A
SCHEMBL9447545 0.80 GAA (0.38) MEN1USP2MAPTALOX15KMT2A
SCHEMBL28351619 0.78 MEN1 (0.42) MEN1USP2MAPTALOX15KMT2A
SCHEMBL10402590 0.77 GAA (0.46) GAANPC1TSHR
SCHEMBL7102659 0.74 RECQL (0.43) MEN1USP2MAPTALOX15KMT2A
SCHEMBL29624830 0.74 RECQL (0.43) MEN1USP2MAPTALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1207869-A2 ANTIMYCOTIC DRUG Novartis AG (CH) 2002-05-29 EP claimed
WO-2001015684-A2 ANTIMYCOTIC DRUG NOVARTIS AG (CH) 2001-03-08 WO claimed
EP-1080722-A1 Antimycotic compositions Novartis AG (CH) 2001-03-07 EP claimed
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2024-07-04 US disclosed
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2024-07-04 US disclosed
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2024-07-04 US disclosed
EP-4326704-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS The University of Stavanger (NO) 2024-02-28 EP disclosed
WO-2022223390-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS THE UNIVERSITY OF STAVANGER (NO) 2022-10-27 WO disclosed
EP-1207869-A2 ANTIMYCOTIC DRUG Novartis AG (CH) 2002-05-29 EP disclosed
WO-2001015684-A2 ANTIMYCOTIC DRUG NOVARTIS AG (CH) 2001-03-08 WO disclosed
EP-1080722-A1 Antimycotic compositions Novartis AG (CH) 2001-03-07 EP disclosed
US-5153224-A Insecticide or pesticide CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed
US-5107017-A Insecticides CIBA-GEIGY CORPORATION (US) 1992-04-21 US disclosed
US-4980506-A Benzoylphenylureas CIBA-GEIGY CORPORATION (US) 1990-12-25 US disclosed
EP-0179022-B1 BENZOYLPHENYL UREAS CIBA-GEIGY AG (CH) 1990-11-07 EP disclosed
EP-0343110-A1 Benzoyl phenyl urea compounds CIBA-GEIGY AG (CH) 1989-11-23 EP disclosed
US-4798837-A Benzoylphenylureas CIBA-GEIGY CORPORATION (US) 1989-01-17 US disclosed
EP-0179022-A2 Benzoylphenyl ureas CIBA-GEIGY AG (CH) 1986-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217917-A1 PHOTOLYTICALLY DEGRADABLE COMPOUNDS AND METHODS DDT, DDC, CTRC MEN1 2480/4885USP2 1204/4885MAPT 2581/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.