SCHEMBL7107856

SCHEMBL7107856

O=S(=O)(Oc1ccc(-c2ncc(OCc3ccccc3)cn2)cc1)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HTM Q9NXG6 1/20 0.45
PPARG P37231 1/20 0.44
CA12 O43570 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 2/20 0.43
GSTP1 P09211 1/20 0.43
PTPRZ1 P23471 1/20 0.43
CA4 P22748 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
ALKBH1 Q13686 1/20 0.43
AR P10275 4/20 0.43
MGLL Q99685 2/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.42
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8167642 0.88 P4HTM (0.40) P4HTMPPARGCA12CA1CA2
SCHEMBL8499207 0.84 CA12 (0.58) PPARGCA12CA1CA2CA9
SCHEMBL28487624 0.82 NPC1 (0.55) CA12CA1CA2CA9NPC1
SCHEMBL28646599 0.80 RAB9A (0.52) P4HTMGSTP1ALKBH1NR4A1NR4A2
SCHEMBL28658874 0.79 ALKBH1 (0.50) P4HTMGSTP1ALKBH1ARNR4A2
SCHEMBL17072088 0.78 GSTP1 (0.56) PPARGCA12CA1CA2CA9
Potassium Ion SCHEMBL28016071 0.78 CA12 (0.55) PPARGCA12CA1CA2CA9
SCHEMBL31083980 0.77 NPC1 (0.49) PPARGCA1CA2CA9NPC1
SCHEMBL6534698 0.77 CYP1A2 (0.62) P4HTMGSTP1ALKBH1NR4A1NR4A2
SCHEMBL7105435 0.77 NPC1 (0.50) NPC1HPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1162406-C Liquid crystal compounds having chiral fluorinated terminal portion 美国3M公司 2004-08-18 CN disclosed
EP-1042302-B1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING & MFG (US) 2003-09-24 EP disclosed
US-6309561-B1 Liquid crystal compounds having a chiral fluorinated terminal portion 3M INNOVATIVE PROPERTIES COMPANY 2001-10-30 US disclosed
CN-1283193-A Liquid crystal compounds having chiral fluorinated terminal portion MINNESOTA MINING & MFG (US) 2001-02-07 CN disclosed
EP-1042302-A1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-10-11 EP disclosed
WO-1999033814-A1 LIQUID CRYSTAL COMPOUNDS HAVING A CHIRAL FLUORINATED TERMINAL PORTION MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-07-08 WO disclosed