Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28646599 | 0.90 | RAB9A (0.52) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL7092038 | 0.89 | LMNA (0.67) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL6534828 | 0.87 | LMNA (0.62) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL7838019 | 0.86 | ESR2 (0.50) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL28658874 | 0.85 | ALKBH1 (0.50) | LMNAMEN1KMT2AALKBH1P4HTM | |
| SCHEMBL8572314 | 0.85 | NPC1 (0.57) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL28643999 | 0.85 | ALKBH1 (0.47) | LMNARAB9ANPC1ALKBH1P4HTM | |
| SCHEMBL2559067 | 0.84 | P4HTM (0.49) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL28652217 | 0.83 | F2 (0.50) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 | |
| SCHEMBL8424909 | 0.83 | NAAA (0.55) | CYP1A2LMNAPTGS1SLC6A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338175-C | Chiral liquid crystal compounds having fluorine-containing terminal moieties | MINNESOTA MINING & MFG (US) | 2007-09-19 | — | — | CN | disclosed |
| US-6737124-B2 | ESPECIALLY DISILANES | DISPLAYTECH, INC. | 2004-05-18 | — | — | US | disclosed |
| CN-1106371-C | Liquid crystal compounds having perfluoroether terminal moieties | MINNESOTA MINING & MFG (US) | 2003-04-23 | — | — | CN | disclosed |
| US-20030003245-A1 | Liquid crystal compounds having a silane tail with a perfluoroalkyl terminal portion | CITIZEN FINETECH MIYOTA CO., LTD. (JP) | 2003-01-02 | — | — | US | disclosed |
| EP-0638112-B1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING & MFG (US) | 2002-08-07 | — | — | EP | disclosed |
| US-6413448-B1 | ESTERS; DOPANTS; LONGER CHIRAL SMECTIC PHASE PITCH; HIGHER TILT ANGLE; LOWER VISCOSITY; CRYSTALLIZATION SUPPRESSION; IMPROVED SOLUBILITY; BROADER C* PHASE TEMPERATURE RANGE | DISPLAYTECH, INC. | 2002-07-02 | — | — | US | disclosed |
| EP-1017757-B1 | FERROELECTRIC LIQUID CRYSTAL DISPLAY PROVIDED WITH ACTIVE- MATRIX ELEMENTS | AVENTIS RES & TECH GMBH & CO (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-6368679-B1 | ENANTIOMORPHS | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-04-09 | — | — | US | disclosed |
| EP-0998541-B1 | CHIP CARD WITH A BISTABLE LIQUID CRYSTAL DISPLAY | AVENTIS RES & TECH GMBH & CO (DE) | 2002-03-13 | — | — | EP | disclosed |
| CN-1326494-A | Chiral liquid crystal compounds having fluorinated terminal portion | MINNESOTA MINING & MFG (US) | 2001-12-12 | — | — | CN | disclosed |
| US-5399291-A | Liquid crystal compounds having a fluoroether terminal portion | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0638112-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5360576-A | Chiral alkenylaryl 2,3-epoxyalkyl ethers, and the use thereof in liquid-crystalline mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-01 | — | — | US | disclosed |
| EP-0618914-A1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993022396-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |
| WO-1993013093-A1 | OXIRANYL METHYL ETHERS EXHIBITING CHIRALITY, AND THEIR USE AS DOPANTS IN LIQUID-CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-08 | — | — | WO | disclosed |
| EP-0540572-A1 | CHIRAL ALKEN-ARYL-2,3-EPOXYALKYL-ETHERS AND THEIR USE IN LIQUID CRYSTAL MIXTURES. | HOECHST AG (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0540571-A1 | Si-CONTAINING, FERROELECTRIC LIQUID CRYSTAL COPOLYMERS, A PROCESS FOR PRODUCING THE SAME, MIXTURES OF THESE COPOLYMERS WITH LOW MOLECULAR WEIGHT LIQUID CRYSTALS AND THEIR USE IN ELECTRO-OPTIC COMPONENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001685-A1 | CHIRAL ALKEN-ARYL-2,3-EPOXYALKYL-ETHERS AND THEIR USE IN LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-06 | — | — | WO | disclosed |
| WO-1992001764-A1 | Si-CONTAINING, FERROELECTRIC LIQUID CRYSTAL COPOLYMERS, A PROCESS FOR PRODUCING THE SAME, MIXTURES OF THESE COPOLYMERS WITH LOW MOLECULAR WEIGHT LIQUID CRYSTALS AND THEIR USE IN ELECTRO-OPTIC COMPONENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030003245-A1 | Liquid crystal compounds having a silane tail with a perfluoroalkyl terminal portion | FFAR3, FFAR1, LPAR1 | CYP1A2 2713/4885LMNA 825/4885PTGS1 4418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.