Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696347 | 0.91 | DNM1 (0.45) | DNM1SPHK1USP2HTT | |
| SCHEMBL14246013 | 0.85 | HSD17B10 (0.37) | TSHRLMNAUSP2 | |
| SCHEMBL14975586 | 0.85 | TSHR (0.42) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11417020 | 0.84 | SPHK1 (0.35) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL4248982 | 0.84 | USP2 (0.39) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL15967789 | 0.81 | TSHR (0.36) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL9117707 | 0.79 | TSHR (0.34) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL13108354 | 0.79 | TSHR (0.34) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL29023673 | 0.79 | LMNA (0.38) | TSHRADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL1835984 | 0.78 | TSHR (0.42) | TSHRADRB2ADRB1ADRB3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6551759-B2 | Multilayer; flexible support, photopolymerizable layer, image recording layer and covering | AGFA-GEVAERT (BE) | 2003-04-22 | — | — | US | disclosed |
| EP-1170121-B1 | Direct-to-plate flexographic printing plate precursor | AGFA GEVAERT (BE) | 2002-06-26 | — | — | EP | disclosed |
| EP-1170121-A1 | Direct-to-plate flexographic printing plate precursor | Agfa-Gevaert naamloze vennootschap (BE) | 2002-01-09 | — | — | EP | disclosed |