SCHEMBL4248982

SCHEMBL4248982

CCCCOC(O)C(O)CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
TSHR P16473 1/20 0.39
ALDH1A1 P00352 3/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
CYP2D6 P10635 2/20 0.36
LMNA P02545 2/20 0.36
CYP3A4 P08684 2/20 0.36
SPHK1 Q9NYA1 1/20 0.36
GMNN O75496 1/20 0.36
POLB P06746 1/20 0.36
THPO P40225 1/20 0.36
MTOR P42345 1/20 0.36
BLM P54132 1/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
MAPT P10636 1/20 0.36
CETP P11597 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27710760 0.93 USP2 (0.47) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL344683 0.91 USP2 (0.50) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL1752697 0.91 USP2 (0.50) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL93727 0.91 USP2 (0.50) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL113020 0.91 USP2 (0.50) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL27547339 0.91 USP2 (0.50) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL3229121 0.86 USP2 (0.38) USP2CYP2D6LMNACYP3A4SPHK1
SCHEMBL7107869 0.84 TSHR (0.36) USP2TSHRALDH1A1CNR1CNR2
SCHEMBL28154318 0.83 ALDH1A1 (0.41) USP2ALDH1A1CNR1CNR2CYP2D6
SCHEMBL14975586 0.83 TSHR (0.42) USP2TSHRALDH1A1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP claimed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN claimed
EP-2810564-B1 Sensation masking composition TAKASAGO INT CORP (USA) (US) 2017-06-14 EP claimed
US-20260034046-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING CATIONIC SURFACTANT AND FATTY ALCOHOL L'OREAL (FR) 2026-02-05 US disclosed
US-20260000602-A1 ANHYDROUS HAIR TREATMENT COMPOSITION L'OREAL (FR) 2026-01-01 US disclosed
EP-3494104-B1 WARMING SENSATION COMPOUNDS TAKASAGO PERFUMERY CO LTD (JP) 2023-11-15 EP disclosed
EP-3510010-B1 TASTE MODULATING ALDEHYDE TAKASAGO PERFUMERY CO LTD (JP) 2023-09-06 EP disclosed
US-11540542-B2 Taste modulating aldehydes TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-01-03 US disclosed
CN-109996778-B Taste modifying aldehydes 高砂香料工业株式会社 2022-12-13 CN disclosed
EP-3984599-A1 ENHANCED PERFUME COMPOSITIONS Takasago International Corporation (JP) 2022-04-20 EP disclosed
CN-109803948-B Warming sensation compound 高砂香料工业株式会社 2022-03-01 CN disclosed
US-8735446-B2 Vanillin acetals and sensory stimulant composition containing the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-05-27 US disclosed
US-20120219512-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-08-30 US disclosed
US-8236970-B2 Vanillin acetals TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-08-07 US disclosed
CN-101218222-B Vanillin acetals and sensory stimulant composition containing the same TAKASAGO PERFUMERY CO LTD 2011-03-23 CN disclosed
US-20090208427-A1 Vanillin Acetals and Sensory Stimulant Composition Containing the Same TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-08-20 US disclosed
CN-101218222-A Vanillin acetals and sensory stimulant composition containing the same TAKASAGO PERFUMERY CO LTD (JP) 2008-07-09 CN disclosed
EP-1902043-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME Takasago International Corporation (JP) 2008-03-26 EP disclosed
WO-2007004740-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-01-11 WO disclosed
US-20060269500-A1 Topical warming composition TAKASAGO INTERNATIONAL CORP. (USA) (US) 2006-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11540542-B2 Taste modulating aldehydes TAS2R10, TAS2R50, TAS2R1 USP2 4146/4885TSHR 1741/4885ALDH1A1 39/4885
US-20060269500-A1 Topical warming composition CUTA, NACA, LSM14A USP2 4194/4885TSHR 3612/4885ALDH1A1 4243/4885
US-20260000602-A1 ANHYDROUS HAIR TREATMENT COMPOSITION TAS2R40, BRDT, APOB USP2 4212/4885TSHR 1183/4885ALDH1A1 1428/4885
US-20120219512-A1 VANILLIN ACETALS AND SENSORY STIMULANT COMPOSITION CONTAINING THE SAME TRPA1, TRPV1, TAS2R5 USP2 1643/4885TSHR 4182/4885ALDH1A1 70/4885
US-20260034046-A1 ANHYDROUS HAIR TREATMENT COMPOSITION COMPRISING CATIONIC SURFACTANT AND FATTY ALCOHOL KRT18, DSG1, PRKDC USP2 4278/4885TSHR 1321/4885ALDH1A1 983/4885
US-20090208427-A1 Vanillin Acetals and Sensory Stimulant Composition Containing the Same TRPA1, TRPV1, TAS2R5 USP2 1643/4885TSHR 4182/4885ALDH1A1 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.