Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108131 | 0.88 | CASP3 (0.43) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1228223 | 0.83 | CES2 (0.64) | ALDH1A1L3MBTL1THRBNPC1RAB9A | |
| SCHEMBL31633615 | 0.83 | CES2 (0.64) | ALDH1A1L3MBTL1THRBNPC1RAB9A | |
| SCHEMBL27999275 | 0.76 | SMN1; SMN2 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15988827 | 0.75 | CTNNB1 (0.54) | ALDH1A1L3MBTL1THRBCES2CES1 | |
| SCHEMBL11829134 | 0.75 | SMN1; SMN2 (0.64) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL287063 | 0.75 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL31390431 | 0.75 | CES2 (0.53) | ALDH1A1L3MBTL1THRBSMN1; SMN2NPC1 | |
| SCHEMBL28274818 | 0.75 | CTNNB1 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27454868 | 0.75 | KMT2A (0.61) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792936-B1 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | MITSUBISHI CHEM CORP (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-5841001-A | ALLOWING 2-HALO-1-(SUBSTITUTED PHENYL)ETHANOL TO CONTACT ENZYME STEREOSELECTIVELY CATALYZING ESTER INTERCHANGE IN PRESENCE OF CARBOXYLIC ANHYDRIDE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0792936-A2 | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol | Mitsubishi Chemical Corporation (JP) | 1997-09-03 | — | — | EP | disclosed |