Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.55 |
| ▸ | MMP13 | P45452 | 13/20 | 0.55 |
| ▸ | MMP1 | P03956 | 12/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764638 | 0.80 | MMP13 (0.67) | MMP2MMP13MMP1 | |
| SCHEMBL7216329 | 0.77 | MMP13 (0.55) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL6774922 | 0.77 | MMP13 (0.67) | MMP2MMP13MMP1 | |
| SCHEMBL7210834 | 0.75 | MMP13 (0.61) | MMP2MMP13MMP1 | |
| SCHEMBL7210567 | 0.75 | MMP2 (0.55) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL7215401 | 0.75 | MMP2 (0.50) | MMP2MMP13MMP1MMP3MMP7 | |
| SCHEMBL6769491 | 0.74 | MMP13 (0.77) | MMP2MMP13MMP1 | |
| SCHEMBL6767563 | 0.74 | MMP13 (0.77) | MMP2MMP13MMP1 | |
| SCHEMBL6767568 | 0.74 | MMP13 (0.77) | MMP2MMP13MMP1 | |
| SCHEMBL7685949 | 0.74 | MMP13 (0.56) | MMP2MMP13MMP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984959-B1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | PHARMACIA CORP (US) | 2003-09-24 | — | — | EP | disclosed |
| US-6362183-B1 | PROTEASE INHIBITORS; RHEUMATIC DISEASES; ANTITUMOR AGENTS | G. D. SEARLE & COMPANY | 2002-03-26 | — | — | US | disclosed |