Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 14/20 | 0.56 |
| ▸ | MMP2 | P08253 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 6/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7685446 | 0.99 | MMP13 (0.56) | MMP13MMP2ALDH1A1HPGDMMP1 | |
| SCHEMBL7690202 | 0.74 | MMP13 (0.65) | MMP13MMP2MMP1 | |
| SCHEMBL7690204 | 0.74 | MMP13 (0.65) | MMP13MMP2MMP1 | |
| SCHEMBL7683904 | 0.74 | MMP13 (0.65) | MMP13MMP2MMP1 | |
| SCHEMBL7108169 | 0.74 | MMP2 (0.55) | MMP13MMP2ALDH1A1HPGDMMP1 | |
| Hydrochloric Acid SCHEMBL7688009 | 0.73 | MMP13 (0.65) | MMP13MMP2MMP1 | |
| Hydrochloric Acid SCHEMBL7688004 | 0.73 | MMP13 (0.65) | MMP13MMP2MMP1 | |
| SCHEMBL3875831 | 0.70 | MMP13 (0.54) | MMP13MMP2ALDH1A1HPGDMMP1 | |
| SCHEMBL3878927 | 0.69 | MMP13 (0.53) | MMP13MMP2ALDH1A1HPGDMMP1 | |
| SCHEMBL7683552 | 0.68 | MMP13 (0.53) | MMP13MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |
| EP-0983258-A4 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO CO (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-0983258-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998039316-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |