SCHEMBL1095484

SCHEMBL1095484

Nc1nc2c(N)cccc2o1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
HSD17B10 Q99714 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HIF1A Q16665 1/20 0.41
ELANE P08246 2/20 0.41
F2RL3 Q96RI0 2/20 0.39
HTR3A P46098 1/20 0.38
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
THRB P10828 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
PIK3CG P48736 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
POLB P06746 2/20 0.34
NR4A2 P43354 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP3A4 P08684 3/20 0.33
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2489345 0.83 ALDH1A1 (0.46) HSD17B10KDM4ESMN1; SMN2ALDH1A1HPGD
SCHEMBL13279633 0.79 SMN1; SMN2 (0.43) MAPTKDM4EHTR3ALMNACYP1A2
SCHEMBL20298203 0.79 BACE1 (0.46) MAPTHSD17B10KDM4EHIF1AELANE
SCHEMBL10984833 0.79 LMNA (0.43) MAPTHTR3ALMNACYP1A2THRB
SCHEMBL288842 0.79 HTR3A (0.36) MAPTELANEHTR3ALMNACYP1A2
SCHEMBL24814788 0.79 HTR3A (0.36) MAPTELANEHTR3ALMNACYP1A2
SCHEMBL288843 0.79 ALDH1A1 (0.43) MAPTKDM4EELANEF2RL3HTR3A
SCHEMBL1041204 0.79 PLAU (0.46) MAPTHSD17B10HIF1AF2RL3HTR3A
SCHEMBL9390262 0.79 ELANE (0.39) MAPTHSD17B10KDM4EHIF1AELANE
SCHEMBL28435873 0.79 ELANE (0.39) MAPTHSD17B10KDM4EHIF1AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119553384-A Preparation method of antistatic modified nylon filament 广东金狮新材科技有限公司 2025-03-04 CN claimed
CN-117810644-B Polyimide lithium ion battery diaphragm and preparation method thereof 深圳市博盛新材料有限公司 2024-04-26 CN claimed
CN-117810644-A Polyimide lithium ion battery diaphragm and preparation method thereof 深圳市博盛新材料有限公司 2024-04-02 CN claimed
CN-112384546-B Thermally conductive resin composition 东洋纺株式会社 2024-01-16 CN claimed
CN-113943262-B Preparation method of 2-aminobenzoxazole compound 烟台海川化学制品有限公司 2022-10-14 CN claimed
US-20040077515-A1 Bis-triazinylaminobenzoxazole derivatives CIBA SPECIALTY CHEMICALS CORP. 2004-04-22 US claimed
EP-1368347-A1 BIS-TRIAZINYLAMINOBENZOXAZOLE DERIVATIVES Ciba SC Holding AG (CH) 2003-12-10 EP claimed
WO-2002066474-A1 BIS-TRIAZINYLAMINOBENZOXAZOLE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-08-29 WO claimed
EP-0789723-B1 POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS MICHIGAN MOLECULAR INST (US) 2001-12-05 EP claimed
US-5985969-A REACTION PRODUCT OF PYROMELLITIC DIANHYDRIDE AND DIAMINO BENZOXAZOLE WITH CHAIN EXTENDERS FOR COATING ON SUBSTRATES THE DOW CHEMICAL COMPANY (US) 1999-11-16 US claimed
US-5919892-A CYCLIZED TO POLYIMIDEBENZOXAZOLE THE DOW CHEMICAL COMPANY (US) 1999-07-06 US claimed
US-5741585-A Polyamic acid precursors and methods for preparing higher molecular weight polyamic acids and polyimidebenzoxazole THE DOW CHEMICAL COMPANY (US) 1998-04-21 US claimed
EP-0822954-A1 POLYAMIC ACID PRECURSORS AND METHOD FOR PREPARING POLYIMIDEBENZOXAZOLE THE DOW CHEMICAL COMPANY (US) 1998-02-11 EP claimed
EP-0789723-A1 POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS THE DOW CHEMICAL COMPANY (US) 1997-08-20 EP claimed
WO-1996034033-A1 POLYAMIC ACID PRECURSORS AND METHOD FOR PREPARING POLYIMIDEBENZOXAZOLE THE DOW CHEMICAL COMPANY (US) 1996-10-31 WO claimed
WO-1996013541-A1 POLYAMIC ACIDS AND METHODS TO CONVERT POLYAMIC ACIDS INTO POLYIMIDEBENZOXAZOLE FILMS THE DOW CHEMICAL COMPANY (US) 1996-05-09 WO claimed
JP-6056992-A None JP disclosed
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES MERCK PATENT GMBH (DE) 2026-04-30 US disclosed
EP-0026474-B1 COMPOSITION AND PROCESS FOR OXIDATIVE DYEING OF HAIR Wella Aktiengesellschaft (DE) 1983-06-08 EP disclosed
JP-H00656992-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077515-A1 Bis-triazinylaminobenzoxazole derivatives FOS, FBL, WDR1 MAPT 3895/4885HSD17B10 2718/4885KDM4E 2163/4885
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES KCNE1, GLRB, PBRM1 MAPT 2622/4885HSD17B10 4058/4885KDM4E 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.