SCHEMBL7108416

SCHEMBL7108416

c1ccc(-c2nc3c(o2)-c2ccccc2-3)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP1 O94782 3/20 0.64
USP19 O94966 2/20 0.64
WDR48 Q8TAF3 1/20 0.64
UCHL3 P15374 1/20 0.49
USP2 O75604 1/20 0.46
USP8 P40818 1/20 0.46
OTUB1 Q96FW1 1/20 0.46
USP36 Q9P275 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.45
NPC1 O15118 4/20 0.45
RAB9A P51151 4/20 0.45
MAPT P10636 4/20 0.44
ALDH1A1 P00352 7/20 0.43
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42
ATAD2 Q6PL18 1/20 0.42
LMNA P02545 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7102799 0.84 USP1 (0.54) USP1USP19WDR48UCHL3USP2
SCHEMBL18203587 0.84 USP1 (0.79) USP1USP19WDR48UCHL3USP2
SCHEMBL18347790 0.84 USP1 (0.79) USP1USP19WDR48UCHL3USP2
SCHEMBL762311 0.79 NR4A2 (0.62) USP1USP19WDR48SMN1; SMN2NPC1
SCHEMBL7808226 0.78 USP1 (1.00) USP1USP19WDR48UCHL3USP2
SCHEMBL29629183 0.78 USP1 (1.00) USP1USP19WDR48UCHL3USP2
SCHEMBL29629184 0.78 USP1 (1.00) USP1USP19WDR48UCHL3USP2
SCHEMBL15489590 0.73 NPC1 (0.50) USP1USP19WDR48UCHL3SMN1; SMN2
Dimethylamine SCHEMBL8172161 0.73 MAPK13 (0.56) USP1USP19WDR48SMN1; SMN2NPC1
SCHEMBL9113400 0.71 MAPK14 (0.61) USP1USP19WDR48UCHL3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004039-B1 METHOD AND SYSTEM FOR RADIOGRAPHIC IMAGING USING GAMMA RAYS AND X-RAY BEAMS BIO SCAN S A (CH) 2003-09-24 EP claimed
US-6552347-B1 Method and device for radiographic imaging using gamma rays and X-ray beams BIO-SCAN S.A. (CH) 2003-04-22 US claimed
EP-1004039-A1 METHOD AND DEVICE FOR RADIOGRAPHIC IMAGING USING GAMMA RAYS AND X-RAY BEAMS Bio-Scan S.A. (CH) 2000-05-31 EP claimed
WO-1999008130-A1 METHOD AND DEVICE FOR RADIOGRAPHIC IMAGING USING GAMMA RAYS AND X-RAY BEAMS BIO - SCAN S.A. (CH) 1999-02-18 WO claimed
US-6552347-B1 Method and device for radiographic imaging using gamma rays and X-ray beams BIO-SCAN S.A. (CH) 2003-04-22 US disclosed
EP-1004039-A1 METHOD AND DEVICE FOR RADIOGRAPHIC IMAGING USING GAMMA RAYS AND X-RAY BEAMS Bio-Scan S.A. (CH) 2000-05-31 EP disclosed
WO-1999008130-A1 METHOD AND DEVICE FOR RADIOGRAPHIC IMAGING USING GAMMA RAYS AND X-RAY BEAMS BIO - SCAN S.A. (CH) 1999-02-18 WO disclosed