SCHEMBL7102799

SCHEMBL7102799

c1ccc(-c2oc3nc2-c2ccccc2-3)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP1 O94782 3/20 0.54
USP19 O94966 2/20 0.54
WDR48 Q8TAF3 1/20 0.54
FABP4 P15090 2/20 0.50
KDM4E B2RXH2 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
GPR55 Q9Y2T6 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NR4A2 P43354 6/20 0.48
FABP3 P05413 1/20 0.48
MAPK13 O15264 1/20 0.46
MAPK12 P53778 1/20 0.46
MAPK11 Q15759 1/20 0.46
MAPK14 Q16539 1/20 0.46
USP2 O75604 1/20 0.43
USP8 P40818 1/20 0.43
OTUB1 Q96FW1 1/20 0.43
USP36 Q9P275 1/20 0.43
RXRA P19793 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108416 0.84 USP1 (0.64) USP1USP19WDR48KDM4ENPC1
SCHEMBL13789731 0.80 CASP3 (0.53) USP1USP19WDR48FABP4KDM4E
SCHEMBL8064764 0.80 RAB9A (0.53) USP1USP19WDR48FABP4KDM4E
SCHEMBL762311 0.79 NR4A2 (0.62) USP1USP19WDR48FABP4KDM4E
SCHEMBL5847041 0.79 KDM4E (0.64) USP1USP19WDR48FABP4KDM4E
SCHEMBL14528596 0.79 NR4A2 (0.56) USP1USP19WDR48FABP4KDM4E
SCHEMBL482742 0.78 MAPK13 (0.45) USP1USP19WDR48FABP4KDM4E
SCHEMBL9007064 0.78 FABP4 (0.52) USP1USP19WDR48FABP4KDM4E
SCHEMBL9428424 0.78 FABP4 (0.61) USP1USP19WDR48FABP4KDM4E
SCHEMBL14528594 0.78 FABP4 (0.49) USP1USP19WDR48FABP4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1004039-B1 METHOD AND SYSTEM FOR RADIOGRAPHIC IMAGING USING GAMMA RAYS AND X-RAY BEAMS BIO SCAN S A (CH) 2003-09-24 EP claimed