Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11733801 | 0.89 | HRH3 (0.52) | HPGDHRH3CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7102647 | 0.88 | KMT2A (0.55) | HPGDHRH3CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL18123508 | 0.85 | HRH3 (0.43) | HPGDHRH3CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL19455128 | 0.83 | HPGD (0.52) | HPGDCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL20869253 | 0.83 | KDM4E (0.59) | HPGDCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL7106738 | 0.83 | HPGD (0.44) | HPGDCYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL21367272 | 0.82 | FOXM1 (0.40) | HPGDHRH3CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL7106735 | 0.81 | HPGD (0.45) | HPGDHRH3ALDH1A1MEN1KMT2A | |
| SCHEMBL19901974 | 0.81 | HRH3 (0.56) | HPGDHRH3ALDH1A1LMNAMAPT | |
| SCHEMBL11519998 | 0.80 | NFE2L2 (0.63) | HPGDCYP1A2CYP2D6CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113005-B1 | Sulfonium salt compounds | WAKO PURE CHEM IND LTD (JP) | 2003-08-06 | — | — | EP | disclosed |
| EP-1238969-A2 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-1113005-A1 | Sulfonium salt compounds | Wako Pure Chemical Industries, Ltd. (JP) | 2001-07-04 | — | — | EP | disclosed |